ROSE-010 is used for the treatment of severe break-through pain associated with Irritable Bowel Syndrome (“IBS”). ROSE-010 has successfully completed two phase 2a trials that showed significant pain relief compared to placebo. IBS is a large indication with few good treatment options for break-through pain episodes. In a meaningful number of cases, patients use opioids to manage pain, which, in addition to the risk of addiction, can cause constipation and exacerbate gastrointestinal issues for IBS sufferers.


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